The Impact of Nucleotides on Specific Immunity

What is Immunity?
Immunity, the body’s self-defense mechanism, is categorized into:

  • Specific Immunity (Adaptive): Acquired through exposure to pathogens or vaccination, offering precise and long-lasting protection.
  • Non-Specific Immunity (Innate): A broad, first-line defense.

Types of Specific Immunity:

  1. Humoral Immunity: B cells produce antibodies that neutralize pathogens.
  2. Cellular Immunity: T cells destroy infected cells and regulate immune responses:
  • — Cytotoxic T Cells (CTLs): Eliminate infected cells.
  • — Helper T Cells (Th cells): Coordinate immune activities.

Role of Nucleotides in Immunity
Researchers conducted a four-week study on mice using Zhen-Ao Biotech nucleotides. Groups included:

  1. Standard feed (control)
  2. Nucleotide-free feed
  3. Feed with varying external nucleotide levels

Findings:

  • Cellular Immunity: Nucleotide deficiency weakened immunity, while supplementation restored and enhanced function.
  • Humoral Immunity: External nucleotides boosted antibody responses, countering deficiencies.

Conclusion: Nucleotides are crucial for maintaining and enhancing specific immunity. Supplementation helps recover and improve immune function when levels are low.

About Zhen-Ao Biotech
Zhen-Ao Biotech specializes in yeast RNA and nucleotide production, recognized globally for quality and innovation. We collaborate with top universities to explore the fascinating potential of nucleotides.

Reference:
Zhang, M., He, J., Jiang, Y., & Xie, Z. Effect of Dietary Nucleotides on Immune Function in Balb/C Mice. Journal of Nutritional Studies, 2023.