What Is Immunity?

Immunity is the body’s self-defense system. It helps protect the body from harmful microorganisms and other external challenges.

There are two main types of immunity:

  • Specific immunity, also called adaptive immunity: develops after exposure to pathogens or vaccination. It provides targeted and longer-lasting protection.
  • Non-specific immunity, also called innate immunity: acts as the body’s broad first-line defense.

Types of Specific Immunity

Specific immunity includes two major branches: humoral immunity and cellular immunity.

Humoral Immunity

Humoral immunity mainly involves B cells. These cells produce antibodies that help neutralize pathogens.

Cellular Immunity

Cellular immunity mainly involves T cells. These cells help destroy infected cells and regulate immune responses.

  • Cytotoxic T cells, also called CTLs: help eliminate infected cells.
  • Helper T cells, also called Th cells: help coordinate immune activities.

The Role of Nucleotides in Immunity

Nucleotides are important molecules involved in cell growth, renewal, and immune function.

Researchers conducted a four-week mouse study using Zhen-Ao Biotech nucleotides. The study compared several groups:

  • Standard feed group, used as the control
  • Nucleotide-free feed group
  • Feed groups with different levels of external nucleotides

Study Findings

Cellular Immunity

The study found that nucleotide deficiency weakened cellular immune function.

However, nucleotide supplementation helped restore and improve this function when levels were low.

Humoral Immunity

The study also found that external nucleotides supported antibody responses.

As a result, supplementation helped counter the effects of nucleotide deficiency.

Conclusion

Nucleotides play an important role in maintaining specific immunity.

When nucleotide levels are low, supplementation may help support immune recovery and normal immune function.

These findings suggest that nucleotides may be valuable nutrients for immune-related nutrition research.

About Zhen-Ao Biotech

Zhen-Ao Biotech specializes in yeast RNA and nucleotide production.

The company works with universities and research partners to explore the nutritional and biological roles of nucleotides.

Reference

Zhang, M., He, J., Jiang, Y., & Xie, Z. Effect of Dietary Nucleotides on Immune Function in Balb/C Mice. Journal of Nutritional Studies, 2023.