Functional Nucleotides
Fully compliant with the newest FCC and GB standards
5′-Nucleotides
Human breast milk naturally contains 5′-nucleotides, including CMP, UMP, AMP, GMP, and IMP. Researchers have reviewed breast milk nucleotide composition and highlighted these mononucleotides as naturally occurring nutritional components in early-life nutrition.
In addition, dietary 5′-nucleotides have attracted scientific interest for their role in infant nutrition, intestinal microbiota development, and immune-related nutritional support. For example, researchers have investigated how nucleotide supplementation may influence formula-fed infant gut microbiota. Therefore, manufacturers should evaluate applications and claims according to the intended market, finished formulation, and local regulatory requirements.
ZABT supplies five individual 5′-nucleotide products:
- Adenosine 5′-Monophosphate
- Cytidine 5′-Monophosphate
- Guanosine 5′-Monophosphate
- Inosine 5′-Monophosphate
- Uridine 5′-Monophosphate
To ensure consistent quality from source to finished ingredient, ZABT uses its self-produced yeast-derived RNA as the starting raw material. Through enzymatic hydrolysis, purification, crystallization, drying, and other controlled processes, we manufacture 5′-nucleotides for food and nutrition applications. Moreover, ZABT manages product quality through its Quality & Research system and designs its production process to meet applicable requirements of the U.S. Food Chemicals Codex (FCC), Chinese GB standards, and relevant EU food regulations.
As a result, customers can use ZABT’s 5′-nucleotides in infant formula, dietary supplements, specialized nutrition products, and other functional nutrition applications. For customized nucleotide combinations, please see our premix and formulation services.
For U.S. infant formula applications, customers should evaluate finished-product compliance under applicable FDA infant formula regulations. Similarly, for EU-market infant formula and follow-on formula applications, customers should confirm compliance with Commission Delegated Regulation (EU) 2016/127 and other applicable EU requirements.
ZABT’s RNA and 5′-nucleotide products also hold Kosher certification from both OU and Badatz.
5′-AMP
Adenosine 5′-Monophosphate Free Acid
Adenosine 5′-Monophosphate Free Acid (5′-Adenylic Acid) is produced using yeast RNA as the raw material, through 5- phosphodiesterase enzymatic hydrolysis, separation, and purification. Adenosine 5′-Monophosphate is colorless and white crystals and is mainly used in nutritional supplements and as a nutrition ingredient for infant formula.
- Also known as 5′-Adenylic Acid, A-5′-P
- Molecular Formula: C10H14N5O7P
- CAS#: 61-19-8
- EINECS: 200-500-0
- Formula Weight: 347.23
| Item | Specification |
|---|---|
| Appearance | Fine White Powder |
| Form | Free Acid |
| Assay(on dry basis) | 98.0% – 102.0% |
| Moisture | ≤ 6.0% |
5′-AMP, 2Na
Adenosine 5′-Monophosphate Disodium Salt
Using yeast ribonucleic acid RNA as the raw material, Adenosine 5′-Monophosphate Disodium Salt is a colorless, white crystal, or a white crystalline powder, 5’-AMP, 2Na mainly used in nutritional supplements and infant formula as a nutrition ingredient.
- Also known as Adenosine 5′-Monophosphoric Acid Disodium Salt
- Molecular Formula: C10H12N5Na2O7P
- CAS#: 4578-31-8
- Formula Weight: 347.23
| Item | Specification |
|---|---|
| Appearance | Fine White Powder |
| Form | Disodium Salt |
| Assay(on dry basis) | 98.0% – 102.0% |
| Moisture | ≤ 25.0% |
5′-CMP
Cytidine 5′-Monophosphate Free Acid
Using yeast ribonucleic acid RNA as the raw material, cytidine 5′-Monophosphate is produced from 5- phosphodiesterase enzymatic hydrolysis, separation, purification, decolorizing, and crystallization. Cytidine 5′-Monophosphate is mainly used in nutritional supplements and infant formula as a food ingredient.
- Also known as 5′-Cytidylic acid, Cytidylate, 5′-CMP, C-5′-P
- Molecular Formula: C9H14N3O8P
- CAS#: 63-37-6
- EINECS: 200-556-6
- Formula Weight: 323.20
| Item | Specification |
|---|---|
| Appearance | Fine White Powder |
| Form | Free Acid |
| Assay(on dry basis) | 98.0% – 102.0% |
| Moisture | ≤ 6.0% |
5′-CMP, 2Na
Cytidine 5′-Monophosphate Disodium Salt
Using yeast ribonucleic acid RNA as the raw material, Cytidine 5′-Monophosphate Disodium Salt exists in colorless or white crystal form, or white crystalline powder, 5’-CMP, 2Na mainly used in nutritional supplements and in infant formula as the nutrition ingredient.
- Also known as 5′-Cytidylic Acid Disodium Salt or DCMP
- Molecular Formula: C9H12N3O8PNa2
- CAS#: 6757-06-8
- Formula Weight: 367.16
| Item | Specification |
|---|---|
| Appearance | Fine White Powder |
| Form | Free Acid |
| Assay(on dry basis) | 98.0% – 102.0% |
| Moisture | ≤ 25.0% |
5′-GMP, 2Na
Guanosine 5′-Monophosphate Disodium Salt
Taking yeast RNA (ribonucleic acid) as the raw material, Guanosine 5′-Monophosphate Disodium Salt exists in colorless or white crystal form, or white crystalline powder, containing about 7 molecules of crystalized water. 5’-GMP, 2Na is mainly used as a flavoring enhancement agent and in infant formula as the nutrition ingredient.
- Also known as 5’-GMP, 5′-Guanylic Acid
- Molecular Formula: C10H12N5Na2O8P
- CAS#: 5550-12-9
- EINECS: 201-598-8
- Formula Weight: 407.18
| Item | Specification |
|---|---|
| Appearance | Fine White Powder |
| Form | Disodium Salt |
| Assay(on dry basis) | 97.0% – 102.0% |
| Moisture | ≤ 25.0% |
5′-IMP, 2Na
Inosine 5′-Monophosphate Disodium Salt
Using yeast ribonucleic acid RNA as the raw material, Inosine 5′-Monophosphate Disodium Salt exists in colorless or white crystal form, or white crystalline powder, containing about 7.5 molecules of crystalized water. 5’-IMP, 2Na is mainly used as flavoring enhancement agents and in infant formula as the nutrition ingredient.
- Also known as 5′-Inosinic acid, Inosinic acid, I-5′-P
- Molecular Formula: C10H13N4O8P
- CAS#: 131-99-7
- EINECS: 205-045-1
- Formula Weight: 392.17
| Item | Specification |
|---|---|
| Appearance | Fine White Powder |
| Form | Disodium Salt |
| Assay(on dry basis) | 97.0% – 102.0% |
| Moisture | ≤ 28.5% |
5′-UMP, 2Na
Uridine 5′-Monophosphate Disodium Salt
Using yeast ribonucleic acid RNA as the raw material, Uridine 5′-Monophosphate Disodium Salt goes through 5- phosphodiesterase enzymatic hydrolysis, separation, purification, decolorizing, and crystallization. 5’-UMP, 2Na contains about 7 molecules of crystalized water, which is mainly used in nutritional supplements and in infant formula as the nutrition ingredient.
- Also known as 5′-Uridylic acid, Uridylic acid, U 5′-P
- Molecular Formula: C9H13N2O9P
- CAS#: 58-97-9
- EINECS: 200-408-0
- Formula weight: 388.15
| Item | Specification |
|---|---|
| Appearance | Fine White Powder |
| Form | Disodium Salt |
| Assay(on dry basis) | 97.0% – 102.0% |
| Moisture | ≤ 25.0% |
5′-Mixed Nucleotides
(Nucleotide complex nutrition enhancer)
NOTE: nucleotide blend can be added maltodextrin or lactose and other carriers according to customer request.
- Mixed Nucleotides Blend (Mixed)
- Nucleotide complex nutrition enhancer
- Proportion is based on per customer’s requirement, please see our premix service.
- All formulas and blend proportions will be classified.
| Item | Specification |
|---|---|
| Appearance | Even distributed white to white-like crystal or crystalline powder, no visible foreign matter |
| Odor | No Odor |
| Assay(on dry basis) | 97.0% – 102.0% |
| Nucleotide(Proportion) | Based on customer’s blend |